Cholesterol esterification tali: o le a lea?

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Cholesterol o se mea taua tele ma tatau i tagata ma manu. I lona vailaʻau, o le lipophilic ava, ma o lea e sili atu saʻo lona taʻua o kolesterol.

Tele o loʻo maua i le tino, ma naʻo sina vaega laʻititi e sau ma meaʻai. E tusa o le afa o le maualuga kolose tulaga e fausia i le ate, e tusa o le ono vaega - i le laititi laiti ma ona sela faapitoa - enterocytes.

Ole vaega itiiti lava ole a tupu i le vailaau o le adrenal glands, o le paʻu lea ma i le tane male fafine

O a aoga ma leaga o le kolose?

Mo nisi mafuaaga, e toʻatele na o latou faʻalogo e uiga i le leaga itu ole kolose.

Ua iloa e tagata uma, a maualuga le plasma, ua tupu se faʻamaʻi e taua o le atherosclerosis.

Ioe, e moni lenei, ae o kolose e tele mea aoga.

O nei aoga lelei o le kolose o:

  1. Cholesterol o se tuʻufaʻatasia o sela membranes;
  2. E fuafua le biochemical meatotino o le sela;
  3. Cholesterol o le muamua vailaʻau, a aunoa ma lea e le mafai ai le faʻatupuina o le bile acid;
  4. Faatasi ai ma le auai saʻo o le kolose, o le tuufaatasiga o tamaloloa ma fafine sex hormone (androgens ma estrogens, faasologa) faia, lea e afaina tonu ai le galuega toe gaosia o le tagata.

Cholesterol e mamao tele mai e leai se aoga, ma le tino e le mafai ona faia e aunoa ma ia. Peitaʻi o lenei faʻavae e matua ese lava, aua i se saʻolotoga mea e seasea lava. Ole mea moni e maua ai i gaʻo gaʻo ile lipoproteins.

E i ai ni ituaiga o lipoproteins - lava maualalo, maualalo, feololo ma maualuga maualuga. O le mea e sili ona lamatia mo le tino o le lipoproteins o maualalo ma e matua tele le maualalo. Ole kolose e fesoʻotaʻi ma i latou e faʻaigoaina "leaga", ma o le faʻateleina o lona totoua e faʻatupuina ai le lafoaia o atherosclerotic faʻailoga i totonu o vaʻa. I le faʻatusatusaga atoatoa, lipoproteins maualuga maualuga e manatu e aoga tele, ma e masani lava o le faʻataʻitaʻiga autu o le togafitiga e faʻamoemoe e faʻateleina le maualuga o le kolose faʻatasi ma i latou.

Afai e oso aʻe le aofai o le low-density lipoprotein kolesterol, atherosclerotic tupe teu amata ona faʻatupulaia faʻasolosolo i puipui o vaʻa. I le aluga o taimi, latou te faateleina i le tele ma sili atu poloka le masani tafe toto.

Le faʻatapulaʻaina o le toto tafe masani e mafai ona faʻaalia ia lava i le tele o faʻailoga: mai taimi faʻapitoa o angina pectoris (tiga o le tiga i tua o le sternum), fatu o le fatu, "intermittent claudication" syndrome, faʻaleagaina faiai ma galuega totino.

O le a le cholesterol est?

Cholesterol esterification o le tali atu a se faʻamalologa o le kolose ma gaʻo gaʻo. O loʻo faʻataʻitaʻiina ina ia aua neʻi oso le kolose i le tuaoi i le va o lipine ma vai. O le tali e mafai ona faatino i totonu o le sela ma fafo atu, ma o loʻo faʻamoemoe e faʻaliliu le kolesterol pe faʻaliliu i se malosi gaioa.

I le taimi o lenei suiga, lecithin faʻatasia ma kolesterol, mafua ai le faʻatuina o lysolecin ma cholesterol. O le faʻagasologa atoa e faʻamauina e se enzyme e taʻua o le LHAT (lecithin cholesterol acyltransferase).

O le gaioiga a lenei enzyme e faʻamoemoe faʻatatau i le anotusi o maualuga maualuga lipoproteins. Faʻaaga le lecithin cholesterol acyltransferase transporter protein, poʻo le apo-protein A1.

O le faʻaiuga o le faia o le esterification, o le ester e faʻaalu atu i totonu lipoprotein maualuga maualuga. Ona o lenei, ua faʻaititia le aofaʻi o le kolose e le faʻatulagaina i fafo atu o le lipoprotein complex, ma ua sauni ai lona i luga mo isi vaega ole gaʻo fua.

E ala mai i le tali atu o le esterification, “lelei” lipoproteins e fesoasoani e faʻasaolotoina sela membranes mai fua saoloto gaʻo, o le mafuaʻaga latou e matua aoga.

Mai le vaʻaiga o le biochemistry, gaʻo gaʻo e pei o linoleic, palmitic ma stearic e tele lava ina aʻafia i le aʻafia.

Mafai ona mafua ai le maualuga ole gaʻo

E pei ona taʻua i luga, e masani ona faʻateleina le maualuga o le kolose.

E mafai ona tele mafuaaga mo lenei.

O taatele o nei:

  • fananau mai (gafa) agavaʻa i tele lapisi;
  • olaga le gaoia;
  • mamafa ova, ae maise lava alualu i luma obesity;
  • le tausia o le meaʻai - soona fiafia i meaai vave, gaʻo, falai, ulaula ma masima meaai;
  • o le i ai o se faamaʻi o le pancreatic e taʻua o le diabetes mellitus, lea e le maalofia ai le tutupu mai o ala faʻasolosolo;
  • e masani ona oso aʻe kolose i tamaloloa nai lo fafine;
  • sili atu le iai o faʻamaʻi luga o le matua o 40 tausaga;
  • soʻo ma faʻafiafia tapaʻa;
  • ava malosi;
  • masani ona popolevale ma faʻaitino;
  • teena ai le masani ai o le faamalosi tino;
  • faʻamaʻi o le ate ma le thyroid gland.

Afai na tupu faʻapea o faʻatoa gaʻo pea kolose i totonu o vaʻa, togafitiga e tatau ona amata vave. O le sitepu muamua o le inuina o anticholesterolemic fualaau.

E mafai ona avea vailaʻau mai le vaega o statins, fibrates, anion-fesuiaiga sequestrants poʻo vailaʻau ma le maualuga mea o nicotinic acid. E taua foi le mulimuli i se taumafataga.

E manaʻomia le faʻaitiitia o gaʻo, falai ma ulaula, meaʻai e maualuga i gaʻo o manu. Nai lo o lea, e fautuaina ia 'ai sili atu legumei, iʻa, aano o manu, meli, flax fatu, meaʻai meaai, kapeti, kapisi mumu, fualaau aina fou ma fua.

Le isi, e tatau ona e amata faʻamalositino masani ma taumafai e faʻaititia le mamafa, pe a iai. Ma le mea moni, e tatau ona faʻatapulaʻaina ituaiga uma o lagona ita, tausisi i fautuaga a fomaʻi ma vaʻavaʻaia lou soifua maloloina.

Ole faʻamatalaga ole kolose o loʻo maua i totonu ole vitio i lenei tusitusiga.

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